McAfee released a version of VirusScan 8.0 that runs on Intel-based Macs, although it uses the Rosetta emulation layer and doesn't have native Intel processor support with a Universal Binary.

McAfee Virex guards against all types of viruses and malicious code, including new and unknown threats, that target OS X. McAfee Virex offers unintrusive, effective protection that hunts down and kills viruses, worms, Trojans, and other malicious code as they attempt to infect systems, allowing users to continue to work uninterrupted. Easy to use and always on guard, McAfee Virex automatically checks for the latest virus updates, so your protection is always up to date. It is supported by McAfee® AVERT® Labs, among the world's top threat research centers.

More info: mcafee.com